In turmeric there is a substance, curcumin, which seems to have a particularly powerful action in the inhibition of cancer cells. This is established by scientists from the University of California at the San Diego School of Medicine, in collaboration with researchers from the University of Beijing and Zhejiang.
Curcumin has long been under observation, previous studies have shown that it is able to interfere with the biochemical processes of cancer cells preventing their proliferation.
The basic problem, however, is that until now the researchers could not find an effective way to allow curcumin to enter the bloodstream. This substance is in fact expelled too quickly to hit the diseased cells.
“In general, curcumin is expelled from the body quickly enough, because it is an effective drug, it needs to be modified to enter the bloodstream and stay in the body long enough to hit the tumor cells and it may not be enough to slow the cancer down. human patients “, says the study.
What’s the news? The team managed to find a way to dissolve curcumin in water and make it effective against tumors.
Curcumin is poorly soluble in water. According to scholarly findings, the platinum-curcumin combination kills cancer cells by fragmenting their DNA. Although the researchers have only tested the administration of curcumin, the contribution of this study to the treatment of the tumor may have new effects also from the probability that the method works with other drugs.
“In cancer therapy, one of the measures that binds a certain number of drugs is their poor solubility,” says Dipanjan Pan, a professor of bioengineering at the University of Illinois at Urbana-Champaign. “Feasibility becomes important only when the drug becomes soluble in water.
“When you want to administer a drug, it must be soluble in water to flow through the bloodstream,” explains one of the researchers, Santosh Misra.
In practice, a system has been created using platinum to make curcumin soluble and to make it more effective against melanoma and breast cancer.
“We found the key to demonstrating the effectiveness of the therapy and solving a long-standing problem with the insolubility of curcumin,” continued Misra.
Curcumin is able to prevent the phosphorylation of STAT3, a transcription factor that leads to the growth of cancer cells and allows them to survive. The combination of curcumin and platinum is able to kill diseased cells by fragmenting their DNA.
Turmeric, is defined as the spice of wonders. With a thousand virtues and benefits it is excellent to be inserted daily in our diet to promote the well-being of the body. The benefits have been known since ancient times, especially in Indian medicine. This important change in science could certainly be a breakthrough, now the team studies how it will be possible to take advantage of this benefit in traditional medicine.